BRAIN Initiative Request for Information (RFI)

The BRAIN Initiative®  aims to develop new tools and technologies to understand and manipulate networks of cells in the brain.  BRAIN 2025: A Scientific Vision  serves as the strategic plan for the BRAIN Initiative at NIH and outlines an overarching vision, seven high level scientific priorities, and many specific goals. Designed to be achieved over at least a decade, the first five years of BRAIN 2025 emphasizes development of tools and technology, and the next five years shifts emphasis to using these tools to make fundamental discoveries about how brain circuits work and what goes wrong in disease.

The BRAIN Initiative is well underway, and we are now approaching the midpoint. At this time, NIH is seeking feedback on the BRAIN Initiative’s progress and on opportunities moving forward given the current state of the science. NIH has established a new BRAIN Initiative Advisory Committee of the NIH Director (ACD) Working Group that will provide scientific guidance to the ACD on how best to continue to accelerate the ambitious vision for the BRAIN Initiative.

The ACD-WG will use the responses to this Request for Information (RFI), along with information gathered through a series of public workshops, to help inform their discussions of the BRAIN Initiative’s progress and potential updates to the plan moving forward.

The purpose of RFI (NOT-NS-18-075) is to solicit input on how best to accomplish the ambitious vision for the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative® set forth in BRAIN 2025: A Scientific Vision. NIH is soliciting input from all interested stakeholders, including members of the scientific community, trainees, academic institutions, the private sector, health professionals, professional societies, advocacy groups, and patient communities, as well as other interested members of the public.

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